4aa5 A 2.38 BS01 NQB A 1 V30 S32 A51 K53 E71 L75 T106 L167 D168 F169 V26 S28 A47 K49 E67 L71 T102 L159 D160 F161 D150 K152 N155 D168 T185 D142 K144 N147 D160 T174 2.7.11.24 0000077,0000165,0000902,0000922,0001502,0001525,0001649,0001890,0002021,0002062,0002862,0004672,0004674,0004707,0004708,0005515,0005524,0005576,0005634,0005654,0005737,0005739,0005829,0006006,0006355,0006357,0006366,0006468,0006915,0006935,0006974,0007165,0007166,0007178,0007519,0010628,0010831,0016301,0016310,0016607,0018105,0019395,0019899,0019903,0030168,0030278,0030316,0031098,0031281,0031663,0032495,0032496,0032735,0032868,0033554,0034774,0035331,0035556,0035924,0035994,0038066,0042307,0042770,0043536,0045648,0045663,0045944,0046323,0046326,0048010,0048273,0048863,0051146,0051149,0051403,0051525,0060045,0060348,0070935,0071222,0071223,0071356,0071479,0071493,0090090,0090336,0090398,0090400,0098586,0098978,0099179,0106310,1900015,1901741,1904813,2000379 ic50=16nM -logKd/Ki=7.80, IC50=16nM IC50=15.85nM Q16539 22608965 1353 RPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP