4a4l A 2.35 BS01 ZN A 1 H93 C212 A328 H55 C174 A290 D176 K178 G180 N181 D194 T214 D138 K140 G142 N143 D156 T176 2.7.11.21 0004672,0005524,0006468 P53350 22154349 1329 EIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIA 4a4l A 2.35 BS02 939 A 1 L59 C67 A80 K82 C133 R134 R136 S137 E140 F183 D194 L21 C29 A42 K44 C95 R96 R98 S99 E102 F145 D156 D176 K178 G180 N181 D194 T214 D138 K140 G142 N143 D156 T176 2.7.11.21 0004672,0005524,0006468 ic50=0.015uM -logKd/Ki=7.82, IC50=0.015uM IC50=15nM P53350 22154349 1331 EIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIA