3zyx A 2.2 BS01 FAD A 1 G11 G13 S15 L33 E34 A35 R36 G41 R42 G57 G58 S59 Y60 P234 V235 I264 W388 Y393 C397 Y398 G425 T426 G434 Y435 M436 A439 G9 G11 S13 L31 E32 A33 R34 G39 R40 G55 G56 S57 Y58 P232 V233 I262 W386 Y391 C395 Y396 G423 T424 G432 Y433 M434 A437 G62 R197 K296 G60 R195 K294 1.4.3.21,1.4.3.4 0005515,0005739,0005740,0005741,0008131,0009055,0009410,0009636,0010044,0010269,0014063,0016491,0019607,0021762,0030425,0032496,0042420,0042802,0043025,0045471,0045964,0048545,0050660,0050665,0051412,0052595,0097621 P27338 21978362 600 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIASTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAATLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTI 3zyx A 2.2 BS02 MBT A 1 L171 A199 Q206 T314 I316 F343 Y398 L169 A197 Q204 T312 I314 F341 Y396 G62 R197 K296 G60 R195 K294 1.4.3.21,1.4.3.4 0005515,0005739,0005740,0005741,0008131,0009055,0009410,0009636,0010044,0010269,0014063,0016491,0019607,0021762,0030425,0032496,0042420,0042802,0043025,0045471,0045964,0048545,0050660,0050665,0051412,0052595,0097621 Ki=0.143uM P27338 21978362 601 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIASTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAATLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTI 3zyx B 2.2 BS01 FAD B 1 V10 G11 G13 S15 L33 E34 A35 R36 G41 R42 G57 G58 S59 Y60 P234 V235 I264 W388 Y393 C397 Y398 G425 T426 G434 Y435 M436 A439 V8 G9 G11 S13 L31 E32 A33 R34 G39 R40 G55 G56 S57 Y58 P232 V233 I262 W386 Y391 C395 Y396 G423 T424 G432 Y433 M434 A437 G62 R197 K296 G60 R195 K294 1.4.3.21,1.4.3.4 0005515,0005739,0005740,0005741,0008131,0009055,0009410,0009636,0010044,0010269,0014063,0016491,0019607,0021762,0030425,0032496,0042420,0042802,0043025,0045471,0045964,0048545,0050660,0050665,0051412,0052595,0097621 P27338 21978362 600 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIASTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAATLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLI 3zyx B 2.2 BS02 MBT B 1 L171 A199 Q206 F343 Y398 L169 A197 Q204 F341 Y396 G62 R197 K296 G60 R195 K294 1.4.3.21,1.4.3.4 0005515,0005739,0005740,0005741,0008131,0009055,0009410,0009636,0010044,0010269,0014063,0016491,0019607,0021762,0030425,0032496,0042420,0042802,0043025,0045471,0045964,0048545,0050660,0050665,0051412,0052595,0097621 Ki=0.143uM P27338 21978362 601 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIASTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAATLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLI