3zno A 2.3 BS01 FAD A 1 I6 G7 A8 G9 I11 A36 D37 R38 T43 T44 T45 A48 G50 L51 K163 V164 C181 T182 W185 R283 H311 G312 G313 Y314 G315 L316 T317 I6 G7 A8 G9 I11 A36 D37 R38 T43 T44 T45 A48 G50 L51 K163 V164 C181 T182 W185 R283 H311 G312 G313 Y314 G315 L316 T317 L51 G313 T317 L51 G313 T317 1.4.3.3 0003884,0005515,0005576,0005737,0005741,0005777,0005782,0005829,0006562,0007586,0016491,0019478,0036088,0042416,0042802,0042995,0045202,0046416,0048786,0055130,0070178,0070945,0071949 P14920 23631755 350 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLS 3zno A 2.3 BS02 SE5 A 1 L56 L215 I223 Y224 Y228 I230 R283 G313 L56 L215 I223 Y224 Y228 I230 R283 G313 L51 G313 T317 L51 G313 T317 1.4.3.3 0003884,0005515,0005576,0005737,0005741,0005777,0005782,0005829,0006562,0007586,0016491,0019478,0036088,0042416,0042802,0042995,0045202,0046416,0048786,0055130,0070178,0070945,0071949 Ki=7.2nM Kd=700nM, Ki=7.2nM, IC50=238nM P14920 23631755 360 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLS 3zno B 2.3 BS01 FAD B 1 I6 G7 A8 G9 V10 I11 A36 D37 R38 T44 T45 A48 G50 L51 V164 T182 W185 R283 G312 G313 Y314 G315 L316 T317 I6 G7 A8 G9 V10 I11 A36 D37 R38 T44 T45 A48 G50 L51 V164 T182 W185 R283 G312 G313 Y314 G315 L316 T317 L51 G313 T317 L51 G313 T317 1.4.3.3 0003884,0005515,0005576,0005737,0005741,0005777,0005782,0005829,0006562,0007586,0016491,0019478,0036088,0042416,0042802,0042995,0045202,0046416,0048786,0055130,0070178,0070945,0071949 P14920 23631755 350 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLS 3zno B 2.3 BS02 SE5 B 1 L51 H217 I223 Y224 Y228 I230 R283 G313 L51 H217 I223 Y224 Y228 I230 R283 G313 L51 G313 T317 L51 G313 T317 1.4.3.3 0003884,0005515,0005576,0005737,0005741,0005777,0005782,0005829,0006562,0007586,0016491,0019478,0036088,0042416,0042802,0042995,0045202,0046416,0048786,0055130,0070178,0070945,0071949 Ki=7.2nM Kd=700nM, Ki=7.2nM, IC50=238nM P14920 23631755 360 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLS