3zjc A 3.15 BS01 MG A 1 S22 T44 S15 T37 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1296 SLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDSLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQLNEEIKLVEEDKHKSEEEKEKEIKLLKLKYDEKIKNIREEAERNIFKDVFNRIWKMLSEIWHRFLSKC 3zjc A 3.15 BS02 GNP A 1 T17 G18 G20 K21 S22 A23 S36 R37 I38 V43 T44 R133 E135 S168 N169 T10 G11 G13 K14 S15 A16 S29 R30 I31 V36 T37 R123 E125 S158 N159 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 -logKd/Ki=5.05, Kd=9uM Q8NHV1 23454188 1297 SLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDSLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQLNEEIKLVEEDKHKSEEEKEKEIKLLKLKYDEKIKNIREEAERNIFKDVFNRIWKMLSEIWHRFLSKC 3zjc B 3.15 BS01 MG B 1 S22 T44 S16 T38 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1294 RSLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQDEKIKNIREEAERNIFKDVFNRIWKMLSEIWHRFLS 3zjc B 3.15 BS02 GNP B 1 G18 S19 G20 K21 S22 A23 S36 R37 I38 V43 R133 E135 S168 N169 G12 S13 G14 K15 S16 A17 S30 R31 I32 V37 R127 E129 S162 N163 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1295 RSLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQDEKIKNIREEAERNIFKDVFNRIWKMLSEIWHRFLS 3zjc C 3.15 BS01 MG C 1 S22 T44 S15 T37 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1294 SLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQLNENIREEAERNIFKDVFNRIWKMLSEIWHRFLS 3zjc C 3.15 BS02 GNP C 1 T17 G18 G20 K21 S22 A23 S36 R37 I38 V43 T44 R133 E135 S168 N169 T10 G11 G13 K14 S15 A16 S29 R30 I31 V36 T37 R126 E128 S161 N162 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1295 SLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQLNENIREEAERNIFKDVFNRIWKMLSEIWHRFLS 3zjc D 3.15 BS01 MG D 1 S22 T44 S14 T36 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1300 LRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNTSKAEKESQVQELVELIEKMVGAYFSDDIYKDTEERLKQRFKDVFNRIWKMLSEIWHRFLSKCKFYS 3zjc D 3.15 BS02 GNP D 1 T17 G18 G20 K21 S22 A23 S36 R37 I38 V43 T44 R133 E135 N169 T9 G10 G12 K13 S14 A15 S28 R29 I30 V35 T36 R120 E122 N156 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1301 LRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNTSKAEKESQVQELVELIEKMVGAYFSDDIYKDTEERLKQRFKDVFNRIWKMLSEIWHRFLSKCKFYS 3zjc E 3.15 BS01 MG E 1 S22 T44 S16 T38 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1298 RSLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQLNEEIKLVESEEEKEKEIKLLKLKYDEKIKNIREEAERNIFKDVFNRIWKMLSEIWHRFLSKCKF 3zjc E 3.15 BS02 GNP E 1 T17 G18 G20 K21 S22 A23 S36 R37 I38 V43 T44 R133 E135 N169 T11 G12 G14 K15 S16 A17 S30 R31 I32 V37 T38 R127 E129 N163 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1299 RSLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQLNEEIKLVESEEEKEKEIKLLKLKYDEKIKNIREEAERNIFKDVFNRIWKMLSEIWHRFLSKCKF 3zjc F 3.15 BS01 MG F 1 S22 T44 S15 T37 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1292 SLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFSLDTTCKEISRCIISSCPGPHAIVLVLQLGYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELESFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQIKLLKLKYDEKIKEEAERNIFKDVFNRIWKMLSEIWHRF 3zjc F 3.15 BS02 GNP F 1 T17 G18 G20 K21 S22 A23 I38 V43 T44 R133 E135 S168 N169 T10 G11 G13 K14 S15 A16 I31 V36 T37 R121 E123 S154 N155 ? 0003924,0005515,0005525,0005737,0005783,0005794,0005811,0042802,0042803,0046039 Q8NHV1 23454188 1293 SLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFSLDTTCKEISRCIISSCPGPHAIVLVLQLGYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELESFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQIKLLKLKYDEKIKEEAERNIFKDVFNRIWKMLSEIWHRF