3wtl A 2.3 BS01 N1Y A 1 Y89 W143 T144 Y185 C187 Y192 Y90 W144 T145 Y186 C188 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM -logKd/Ki=7.04, Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl A 2.3 BS02 N1Y E 1 W53 R104 L112 M114 W54 R105 L113 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM -logKd/Ki=7.04, Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl B 2.3 BS01 N1Y A 1 W53 R104 L112 M114 W54 R105 L113 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM -logKd/Ki=7.04, Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl B 2.3 BS02 N1Y B 1 Y89 W143 Y185 C187 Y192 Y90 W144 Y186 C188 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM -logKd/Ki=7.04, Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl C 2.3 BS01 N1Y B 1 W53 R104 L112 M114 W54 R105 L113 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl C 2.3 BS02 N1Y C 1 W143 Y185 W144 Y186 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl D 2.3 BS01 N1Y C 1 W53 Q55 R104 L112 Y113 M114 W54 Q56 R105 L113 Y114 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl D 2.3 BS02 N1Y D 1 Y89 W143 T144 Y185 C187 Y192 Y90 W144 T145 Y186 C188 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl E 2.3 BS01 N1Y D 1 W53 R104 L112 M114 W54 R105 L113 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtl E 2.3 BS02 N1Y E 1 Y89 W143 T144 Y185 C187 Y192 Y90 W144 T145 Y186 C188 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.092uM Ki=80nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS