3wtj A 2.24 BS01 TH4 A 1 Y89 W143 T144 T184 Y185 C187 C188 Y192 Y90 W144 T145 T185 Y186 C188 C189 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM -logKd/Ki=6.53, Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtj A 2.24 BS02 TH4 E 1 R104 M114 R105 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM -logKd/Ki=6.53, Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtj B 2.24 BS01 TH4 A 1 R104 M114 R105 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM -logKd/Ki=6.53, Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtj B 2.24 BS02 TH4 B 1 Y89 W143 T184 Y185 C187 Y192 Y90 W144 T185 Y186 C188 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM -logKd/Ki=6.53, Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtj C 2.24 BS01 TH4 C 1 Y89 W143 T144 T184 Y185 C187 C188 Y192 Y90 W144 T145 T185 Y186 C188 C189 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtj D 2.24 BS01 TH4 C 1 R104 L112 M114 R105 L113 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtj D 2.24 BS02 TH4 D 1 Y89 W143 T144 T184 Y185 C187 C188 Y192 Y90 W144 T145 T185 Y186 C188 C189 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtj E 2.24 BS01 TH4 D 1 R104 L112 M114 R105 L113 M115 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3wtj E 2.24 BS02 TH4 E 1 W143 T144 T184 Y185 C187 C188 Y192 W144 T145 T185 Y186 C188 C189 Y193 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Kd=0.297uM Ki=220nM P58154 25267717 301 AADRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWDSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS