3wf6 A 2.031 BS01 ZN A 1 C240 H245 H251 C254 C144 H149 H155 C158 D218 K220 E222 N223 D236 T256 D122 K124 E126 N127 D140 T160 2.7.11.1 0004672,0004674,0005524,0006468 P23443 25078151 401 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 3wf6 A 2.031 BS02 FZ9 A 1 G98 G100 V105 A121 E173 L175 M225 K241 G14 G16 V21 A37 E77 L79 M129 K145 D218 K220 E222 N223 D236 T256 D122 K124 E126 N127 D140 T160 2.7.11.1 0004672,0004674,0005524,0006468 ic50=33nM -logKd/Ki=7.48, IC50=33nM P23443 25078151 402 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ