3wf5 A 2.099 BS01 ZN A 1 C240 H245 H251 C254 C144 H149 H155 C158 D218 K220 E222 N223 D236 T256 D122 K124 E126 N127 D140 T160 2.7.11.1 0004672,0004674,0005524,0006468 P23443 25078151 401 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 3wf5 A 2.099 BS02 FZ8 A 1 K99 G100 V105 A121 E173 L175 K241 K15 G16 V21 A37 E77 L79 K145 D218 K220 E222 N223 D236 T256 D122 K124 E126 N127 D140 T160 2.7.11.1 0004672,0004674,0005524,0006468 ic50=81nM -logKd/Ki=7.09, IC50=81nM P23443 25078151 402 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ