3vzc A 2.3 BS01 UUL A 1 F173 I174 V177 D178 T196 M272 F288 L299 F303 M306 H311 F168 I169 V172 D173 T187 M255 F271 L282 F286 M289 H294 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 Ki=16000nM, IC50=35000nM Q9NYA1 23602659 1001 MGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 3vzc B 2.3 BS01 UUL B 1 F173 I174 V177 D178 T196 L268 M272 F288 F303 M306 F165 I166 V169 D170 T184 L244 M248 F264 F279 M282 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 Ki=16000nM, IC50=35000nM Q9NYA1 23602659 1001 GVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRMRFTLGTFLRLAALRTYRGRLAYLPVGRVQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 3vzc C 2.3 BS01 UUL C 1 F173 I174 V177 D178 T196 L268 M272 F288 F303 M306 H311 F168 I169 V172 D173 T187 L246 M250 F266 F281 M284 H289 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 Ki=16000nM, IC50=35000nM Q9NYA1 23602659 1001 MGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRMRFTLGTFLRLAALRTYRGRLAYLPVGRQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 3vzc D 2.3 BS01 UUL D 1 F173 I174 V177 D178 T196 M272 F288 L299 F303 M306 H311 F168 I169 V172 D173 T187 M256 F272 L283 F287 M290 H295 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 Ki=16000nM, IC50=35000nM Q9NYA1 23602659 1001 MGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 3vzc E 2.3 BS01 UUL E 1 F173 I174 V177 D178 T196 L259 L268 M272 F288 F303 M306 F166 I167 V170 D171 T185 L237 L246 M250 F266 F281 M284 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 Ki=16000nM, IC50=35000nM Q9NYA1 23602659 1001 SGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRMRFTLGTFLRLAALRTYRGRLAYLPVGRVGQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 3vzc F 2.3 BS01 UUL F 1 F173 I174 D178 T196 M272 F288 F303 M306 H311 F168 I169 D173 T187 M252 F268 F283 M286 H291 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 Ki=16000nM, IC50=35000nM Q9NYA1 23602659 1001 MGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRMRFTLGTFLRLAALRTYRGRLAYLPVGRVGQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG