3vth A 2.0 BS01 ZN A 1 C114 C117 C136 C139 C112 C115 C134 C137 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 801 RGRVPQIQARQINIFGIVQGVGFRPFVFNIAQKYNLKGIVYNNSSGLYIEVEGEEKDIEAFIREIKENPPSLSVIDEIQVREVEVKEYKDFKIVGSKEDGGFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPMCEKCSREYHDPHDRRFHAQPVACFDCGPSLSFVGEGCFDDEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth A 2.0 BS02 ZN A 2 C164 C167 C186 C189 C162 C165 C184 C187 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 802 RGRVPQIQARQINIFGIVQGVGFRPFVFNIAQKYNLKGIVYNNSSGLYIEVEGEEKDIEAFIREIKENPPSLSVIDEIQVREVEVKEYKDFKIVGSKEDGGFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPMCEKCSREYHDPHDRRFHAQPVACFDCGPSLSFVGEGCFDDEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth A 2.0 BS03 APC A 1 K245 R247 K250 P251 L285 T303 T328 S329 E334 R382 K243 R245 K248 P249 L283 T301 T326 S327 E332 R380 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 804 RGRVPQIQARQINIFGIVQGVGFRPFVFNIAQKYNLKGIVYNNSSGLYIEVEGEEKDIEAFIREIKENPPSLSVIDEIQVREVEVKEYKDFKIVGSKEDGGFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPMCEKCSREYHDPHDRRFHAQPVACFDCGPSLSFVGEGCFDDEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth A 2.0 BS04 AP2 A 1 Y409 H483 H487 D507 G508 T509 F601 E617 A621 G702 N706 N733 D734 Y407 H481 H485 D505 G506 T507 F599 E615 A619 G700 N704 N731 D732 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 806 RGRVPQIQARQINIFGIVQGVGFRPFVFNIAQKYNLKGIVYNNSSGLYIEVEGEEKDIEAFIREIKENPPSLSVIDEIQVREVEVKEYKDFKIVGSKEDGGFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPMCEKCSREYHDPHDRRFHAQPVACFDCGPSLSFVGEGCFDDEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth A 2.0 BS05 FE A 1 H483 H487 D507 D734 H481 H485 D505 D732 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 807 RGRVPQIQARQINIFGIVQGVGFRPFVFNIAQKYNLKGIVYNNSSGLYIEVEGEEKDIEAFIREIKENPPSLSVIDEIQVREVEVKEYKDFKIVGSKEDGGFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPMCEKCSREYHDPHDRRFHAQPVACFDCGPSLSFVGEGCFDDEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth A 2.0 BS06 PO4 A 1 H462 E545 H460 E543 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 811 RGRVPQIQARQINIFGIVQGVGFRPFVFNIAQKYNLKGIVYNNSSGLYIEVEGEEKDIEAFIREIKENPPSLSVIDEIQVREVEVKEYKDFKIVGSKEDGGFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPMCEKCSREYHDPHDRRFHAQPVACFDCGPSLSFVGEGCFDDEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth B 2.0 BS01 PO4 A 1 K463 K472 K338 K347 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 811 GFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPSREYHDPHDRRFHAQPVAEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth B 2.0 BS02 ZN B 1 C114 C117 C136 C139 C12 C15 C34 C37 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 802 GFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPSREYHDPHDRRFHAQPVAEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth B 2.0 BS03 APC B 1 K245 R247 K250 P251 L285 T303 L304 T328 S329 S333 E334 R382 K120 R122 K125 P126 L160 T178 L179 T203 S204 S208 E209 R257 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 804 GFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPSREYHDPHDRRFHAQPVAEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth B 2.0 BS04 AP2 B 1 Y409 H483 H487 D507 G508 T509 F601 E617 A621 G702 N706 N733 D734 Y284 H358 H362 D382 G383 T384 F476 E492 A496 G577 N581 N608 D609 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 806 GFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPSREYHDPHDRRFHAQPVAEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS 3vth B 2.0 BS05 FE B 1 H483 H487 D507 D734 H358 H362 D382 D609 3.6.1.7,6.2.-.- 0003725,0003998,0008270,0016743,0016787,0016874,0046872,0046944,0051604 Q8RDB0 22740694 807 GFVPVSPDMGVCEDCLRELKDPKDRRYRYPFINCTNCGPRFSIIEDIPYDRAKTSMKVFPSREYHDPHDRRFHAQPVAEIKCVAKALKEGKIVAIKGIGGFHLAVNALDDEAVATLRRRKKRYGKPFAVMMRDVEEVKKYCIVSPEEERLLLSQRRPIVLLKKKGEKLAKGIADDLDTLGVMLPYAPIHYLLMEEIDFPIVMTSGNVSEEPICKDNEEALEKLKDIADVFLLNNRDIVNRIDDSVTSFNAGAERIIRRARGYAPQPILLKKEVKASILAVGGFYKNTFCMTKGHYAFISHHIGDLDNEKAFNYYIEQIERYKKLFRVDPEVVAHDMHKGYLSTQYAKSLDLPKIEVQHHHAHIASCMAEHNLDEKVIGIAYDGTGYGTDGNVWGAEILVCDLKSFERIAHLKYKPLPGNELAIKKIYRTALGFIFDNISFYKNFVEQVDSRELDIILKQIDRKINTAYVSSMGRFFDAVAALIGVRKEVLFEGQAAMELESLMAESEEYYEYEILKEDRYVIDPELILRQIYEDYMKGFEKSYISAKFHNTVVNFTYDLANLIRKETGINKVVLSGGSFQNRYLLRRLIEKLSLSGFEVYSNSKVPCNDGGISLGQAVIANKILEGSAWS