3vqh A 1.95 BS01 peptide B 0 S53 Q84 E127 F129 R133 K168 E170 F187 G200 E203 E230 Y235 P236 F239 A240 D241 I246 D328 Y330 S50 Q81 E124 F126 R130 K165 E167 F184 G197 E200 E227 Y232 P233 F236 A237 D238 I243 D325 Y327 D166 K168 E170 N171 D184 T201 D163 K165 E167 N168 D181 T198 2.7.11.11 0000287,0001669,0001707,0001843,0002027,0003091,0004672,0004674,0004679,0004691,0004712,0005515,0005524,0005634,0005654,0005737,0005739,0005759,0005813,0005829,0005886,0005930,0005952,0006397,0006468,0006611,0007189,0007193,0010737,0010881,0016241,0016310,0016607,0018105,0019221,0019901,0019904,0030145,0031410,0031514,0031594,0031625,0032024,0032703,0034237,0034380,0034605,0034704,0035694,0036126,0044853,0045542,0045667,0045722,0045879,0046827,0048240,0048471,0050804,0050850,0051726,0055117,0061136,0070062,0070417,0070613,0071333,0071374,0071377,0071872,0086064,0097546,0098794,0098978,0099103,0099170,0106310,1903779,1904262,1904539,1990044,2000810 P17612 22869112 5 ~ 24 AAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 3vqh A 1.95 BS02 IQB A 1 L49 G50 T51 G52 F54 V57 A70 M120 V123 E127 E170 L173 T183 D184 F327 L46 G47 T48 G49 F51 V54 A67 M117 V120 E124 E167 L170 T180 D181 F324 D166 K168 E170 N171 D184 T201 D163 K165 E167 N168 D181 T198 2.7.11.11 0000287,0001669,0001707,0001843,0002027,0003091,0004672,0004674,0004679,0004691,0004712,0005515,0005524,0005634,0005654,0005737,0005739,0005759,0005813,0005829,0005886,0005930,0005952,0006397,0006468,0006611,0007189,0007193,0010737,0010881,0016241,0016310,0016607,0018105,0019221,0019901,0019904,0030145,0031410,0031514,0031594,0031625,0032024,0032703,0034237,0034380,0034605,0034704,0035694,0036126,0044853,0045542,0045667,0045722,0045879,0046827,0048240,0048471,0050804,0050850,0051726,0055117,0061136,0070062,0070417,0070613,0071333,0071374,0071377,0071872,0086064,0097546,0098794,0098978,0099103,0099170,0106310,1903779,1904262,1904539,1990044,2000810 -logKd/Ki=5.92, IC50=1.2uM Ki=48nM P17612 22869112 401 AAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF