3ua9 A 2.15 BS01 ZN A 1 C1081 H1084 C1089 C1092 C130 H133 C138 C141 2.4.2.-,2.4.2.30 0003950 Q9H2K2 22233320 1 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 3ua9 A 2.15 BS02 IWR A 1 F1035 A1038 G1043 F1044 D1045 H1048 Y1050 Y1060 Y1071 F84 A87 G92 F93 D94 H97 Y99 Y109 Y120 2.4.2.-,2.4.2.30 0003950 -logKd/Ki=7.25, IC50=56nM IC50=135nM Q9H2K2 22233320 2 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 3ua9 B 2.15 BS01 ZN B 1 C1081 H1084 C1089 C1092 C130 H133 C138 C141 2.4.2.-,2.4.2.30 0003950 Q9H2K2 22233320 2 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 3ua9 B 2.15 BS02 IWR B 1 F1035 A1038 G1043 F1044 D1045 H1048 Y1050 G1058 I1059 Y1060 Y1071 I1075 F84 A87 G92 F93 D94 H97 Y99 G107 I108 Y109 Y120 I124 2.4.2.-,2.4.2.30 0003950 IC50=135nM Q9H2K2 22233320 1 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE