3u8h A 2.3 BS01 BHP A 1 L2 F5 H6 A17 G22 G29 V30 G31 C44 H47 D48 Y51 L2 F5 H6 A17 G22 G29 V30 G31 C44 H47 D48 Y51 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 -logKd/Ki=6.49, IC50=0.32uM P14555 23482564 125 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 3u8h A 2.3 BS02 CA A 1 F23 Y24 G25 Y112 N114 F23 Y24 G25 Y112 N114 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 23482564 126 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 3u8h A 2.3 BS03 CA A 2 H27 G29 G31 D48 H27 G29 G31 D48 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 23482564 127 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 3u8h A 2.3 BS04 BHP B 1 A18 F23 A18 F23 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 -logKd/Ki=6.49, IC50=0.32uM P14555 23482564 125 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 3u8h B 2.3 BS01 BHP A 1 F23 V30 F23 V30 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 23482564 125 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 3u8h B 2.3 BS02 BHP B 1 F5 A17 G29 G31 C44 H47 D48 Y51 F5 A17 G29 G31 C44 H47 D48 Y51 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 23482564 125 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 3u8h B 2.3 BS03 CA B 1 F23 G25 Y112 N114 F23 G25 Y112 N114 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 23482564 126 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 3u8h B 2.3 BS04 CA B 2 H27 G29 G31 D48 H27 G29 G31 D48 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 23482564 127 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC