3tz4 A 2.25 BS01 ADP A 1 N249 A253 I290 V298 T304 T305 G335 G337 G339 L340 N212 A216 I253 V261 T267 T268 G270 G272 G274 L275 Y241 E245 K248 N249 Y204 E208 K211 N212 2.7.11.1,2.7.11.4 0004672,0004674,0004722,0004740,0005524,0005739,0005759,0006550,0006552,0006574,0007283,0008610,0009083,0010906,0016301,0016310,0016772,0045252,0047323,0106310 Q00972 23716694 389 VRLTPTMMLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDG 3tz4 A 2.25 BS02 03H A 1 I72 Y99 H132 R167 I170 R171 I35 Y62 H95 R130 I133 R134 Y241 E245 K248 N249 Y204 E208 K211 N212 2.7.11.1,2.7.11.4 0004672,0004674,0004722,0004740,0005524,0005739,0005759,0006550,0006552,0006574,0007283,0008610,0009083,0010906,0016301,0016310,0016772,0045252,0047323,0106310 -logKd/Ki=5.49, Kd=3.2uM Q00972 23716694 390 VRLTPTMMLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDG