3te7 A 1.7 BS01 ZN A 1 H173 H177 C222 H172 H176 C221 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 21859103 231 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3te7 A 1.7 BS02 FAD A 1 H11 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 R200 H10 S15 F16 N17 S19 P101 L102 Y103 W104 F105 T146 T147 G148 G149 Y154 E192 R199 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 21859103 232 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3te7 A 1.7 BS03 TE7 A 1 F126 F178 F125 F177 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 ic50=59nM IC50=3200nM P16083 21859103 1 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3te7 A 1.7 BS04 TE7 B 1 W105 F106 E193 W104 F105 E192 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 ic50=59nM IC50=3200nM P16083 21859103 1 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3te7 B 1.7 BS01 TE7 A 1 W105 F106 W104 F105 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 ic50=59nM IC50=3200nM P16083 21859103 1 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3te7 B 1.7 BS02 TE7 B 1 F126 F178 F125 F177 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 ic50=59nM IC50=3200nM P16083 21859103 1 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3te7 B 1.7 BS03 ZN B 1 H173 H177 C222 H172 H176 C221 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 21859103 231 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3te7 B 1.7 BS04 FAD B 1 H11 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 R200 H10 S15 F16 N17 S19 P101 L102 Y103 W104 F105 T146 T147 G148 G149 Y154 E192 R199 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 21859103 232 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG