3skc A 3.2 BS01 BR2 A 1 A481 K483 L505 L514 I527 T529 W531 C532 D594 A34 K36 L58 L67 I80 T82 W84 C85 D147 D576 K578 N580 N581 D594 S616 D129 K131 N133 N134 D147 S153 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=8.80, IC50=1.6nM P15056 21802293 801 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPK 3skc B 3.2 BS01 BR2 B 1 A481 K483 L505 L514 F516 I527 T529 W531 C532 F583 D594 F595 G596 A34 K36 L58 L67 F69 I80 T82 W84 C85 F136 D147 F148 G149 D576 K578 N580 N581 D594 S616 D129 K131 N133 N134 D147 S169 2.7.11.1 0004672,0005524,0006468 P15056 21802293 801 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPK