3s5y A 2.105 BS01 FUC C 1 F149 N179 F118 N148 D170 D231 D139 D200 3.2.1.22 0003824,0004553,0004557,0005102,0005515,0005576,0005737,0005764,0005794,0005975,0006629,0009311,0016139,0016787,0016798,0016936,0019915,0030168,0030431,0031133,0035578,0042803,0043202,0045019,0046477,0046479,0051001,0070062,0070527,0090325 P06280 22195554 7 LDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTM 3s5y A 2.105 BS02 DGJ A 1 W47 D92 D93 C142 K168 D170 E203 R227 D231 W16 D61 D62 C111 K137 D139 E172 R196 D200 D170 D231 D139 D200 3.2.1.22 0003824,0004553,0004557,0005102,0005515,0005576,0005737,0005764,0005794,0005975,0006629,0009311,0016139,0016787,0016798,0016936,0019915,0030168,0030431,0031133,0035578,0042803,0043202,0045019,0046477,0046479,0051001,0070062,0070527,0090325 Ki=39nM -logKd/Ki=7.41, Ki=39.1nM IC50=70nM P06280 22195554 801 LDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTM 3s5y B 2.105 BS01 XYP F 1 D33 R38 D2 R7 D170 D231 D139 D200 3.2.1.22 0003824,0004553,0004557,0005102,0005515,0005576,0005737,0005764,0005794,0005975,0006629,0009311,0016139,0016787,0016798,0016936,0019915,0030168,0030431,0031133,0035578,0042803,0043202,0045019,0046477,0046479,0051001,0070062,0070527,0090325 P06280 22195554 4 LDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTMQ 3s5y B 2.105 BS02 DGJ B 1 W47 D92 D93 C142 K168 D170 E203 R227 D231 W16 D61 D62 C111 K137 D139 E172 R196 D200 D170 D231 D139 D200 3.2.1.22 0003824,0004553,0004557,0005102,0005515,0005576,0005737,0005764,0005794,0005975,0006629,0009311,0016139,0016787,0016798,0016936,0019915,0030168,0030431,0031133,0035578,0042803,0043202,0045019,0046477,0046479,0051001,0070062,0070527,0090325 Ki=39nM -logKd/Ki=7.41, Ki=39.1nM IC50=70nM P06280 22195554 802 LDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTMQ