3qxv A 2.5 BS01 MTX A 1 V4 A26 S30 S31 W34 M36 R74 N76 Y79 L80 V81 V1 A23 S27 S28 W31 M33 R71 N73 Y76 L77 V78 Kd=5nM -logKd/Ki=8.40, Kd=4nM 21557375 2000 VQLVESGGGLVQAGGSLRLSCAASRRSSRSWAMAWFRQAPGKEREFVAKISGDGRLTTYGDSVKGRFTISRDNAEYLVYLQMDSLKPEDTAVYYCAADDNYVTASWRSGPDYWGQGTQVTVSS 3qxv B 2.5 BS01 MTX B 1 V4 A26 R28 S30 S31 W34 D75 Y79 L80 V81 Y120 V1 A23 R25 S27 S28 W31 D72 Y76 L77 V78 Y112 Kd=5nM 21557375 2000 VQLVESGGGLVQAGGSLRLSCAASRRSSRSWAMAWFRQAPGKEREFVAKISGDGRLTTYGDSVKGRFTISRDNAEYLVYLQMDSLKPEDTAVYYCAADDNYVTASWRSGPDYWGQGTQVTVSS 3qxv C 2.5 BS01 MTX C 1 V4 A26 R28 S30 W34 M36 R74 Y79 L80 V81 V1 A23 R25 S27 W31 M33 R71 Y76 L77 V78 Kd=5nM 21557375 2000 VQLVESGGGLVQAGGSLRLSCAASRRSSRSWAMAWFRQAPGKEREFVAKISGDGRLTTYGDSVKGRFTISRDNAEYLVYLQMDSLKPEDTAVYYCAADDNYVTASWRSGPDYWGQGTQVTVSS 3qxv D 2.5 BS01 MTX D 1 V4 A26 R28 S30 S31 W34 R74 N76 Y79 L80 V81 Y120 V2 A24 R26 S28 S29 W32 R72 N74 Y77 L78 V79 Y113 Kd=5nM 21557375 2000 QVQLVESGGGLVQAGGSLRLSCAASRRSSRSWAMAWFRQAPGKEREFVAKISGDGRLTTYGDSVKGRFTISRDNAEYLVYLQMDSLKPEDTAVYYCAADDNYVTASWRSGPDYWGQGTQVTVSS 3qxv E 2.5 BS01 MTX E 1 C24 R28 S30 S31 W34 M36 Y79 L80 Y120 C17 R21 S23 S24 W27 M29 Y69 L70 Y104 Kd=5nM 21557375 2000 VQLVESGQAGGSLRLSCAASRRSSRSWAMAWFRAKEREFVAKISGDGRLTTYGDSVKGRFTISRDNAEYLVYLQMDLKPEDTAVYYCAADDNYVTASWRSGPDYWGQGTQVTV