3qrj A 1.82 BS01 919 A 1 L248 A269 E282 E286 M290 I315 F317 M318 L370 A380 D381 F382 L15 A36 E44 E48 M52 I77 F79 M80 L132 A142 D143 F144 D363 A365 R367 N368 D381 P402 D125 A127 R129 N130 D143 P164 2.7.10.2 0004672,0004713,0005524,0006468 ic50=4nM -logKd/Ki=8.40, IC50=4nM P00519 21481795 2 KWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIIIEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 3qrj B 1.82 BS01 919 B 1 L248 A269 E282 E286 M290 V299 F317 M318 L370 A380 D381 F382 L16 A37 E50 E54 M58 V67 F85 M86 L138 A148 D149 F150 D363 A365 R367 N368 D381 P402 D131 A133 R135 N136 D149 P170 2.7.10.2 0004672,0004713,0005524,0006468 ic50=4nM P00519 21481795 1 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIIIEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMF