3qfv A 2.65 BS01 NM7 A 1 I82 G83 V90 T137 M153 Y156 F370 I81 G82 V89 T136 M152 Y155 F369 D200 K202 N205 D218 T239 D199 K201 N204 D217 T238 2.7.11.1 0004672,0004674,0005524,0006468 -logKd/Ki=5.77, IC50=1.69uM Q9Y5S2 21949762 416 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVSGLHLPFIGFTFTTESCFSDRGSL 3qfv B 2.65 BS01 NM7 B 1 V90 T137 M153 Y155 Y156 L207 F370 V89 T136 M152 Y154 Y155 L206 F369 D200 K202 N205 D218 T239 D199 K201 N204 D217 T238 2.7.11.1 0004672,0004674,0005524,0006468 Q9Y5S2 21949762 416 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDGFSGLHLPFIGFTFTTESCFSDRGSL 3qfv B 2.65 BS02 MG B 1 H198 D218 F219 G220 S221 C222 H197 D217 F218 G219 S220 C221 D200 K202 N205 D218 T239 D199 K201 N204 D217 T238 2.7.11.1 0004672,0004674,0005524,0006468 Q9Y5S2 21949762 419 SAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDGFSGLHLPFIGFTFTTESCFSDRGSL