3q8h A 1.75 BS01 ZN A 1 D10 H12 H44 D10 H12 H44 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q63T71 24157367 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3q8h A 1.75 BS02 AO9 A 1 H36 D58 I59 G60 F63 H36 D58 I59 G60 F63 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 -logKd/Ki=4.15, Kd=70uM Q63T71 24157367 165 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3q8h A 1.75 BS03 AO9 A 2 L107 A108 A133 L99 A100 A125 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 -logKd/Ki=4.15, Kd=70uM Q63T71 24157367 164 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3q8h B 1.75 BS01 AO9 A 1 K106 L107 A108 A133 K102 L103 A104 A129 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 -logKd/Ki=4.15, Kd=70uM Q63T71 24157367 165 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3q8h B 1.75 BS02 ZN B 1 D10 H12 H44 D10 H12 H44 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q63T71 24157367 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3q8h B 1.75 BS03 AO9 B 1 H36 D58 I59 G60 F63 H36 D58 I59 G60 F63 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 -logKd/Ki=4.15, Kd=70uM Q63T71 24157367 165 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 3q8h C 1.75 BS01 AO9 A 2 H36 D58 G60 H36 D58 G60 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q63T71 24157367 164 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVR 3q8h C 1.75 BS02 AO9 B 1 K106 L107 A108 A133 K106 L107 A108 A133 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q63T71 24157367 165 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVR 3q8h C 1.75 BS03 ZN C 1 D10 H12 H44 D10 H12 H44 4.6.1.12 0008299,0008685,0016114,0016829,0019288,0046872 Q63T71 24157367 163 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVR