3pkd A 1.47 BS01 MN A 1 D142 H205 T236 E238 E269 D139 H202 T233 E235 E266 H114 D131 D142 G204 H205 G208 H212 L215 E238 N242 E269 H111 D128 D139 G201 H202 G205 H209 L212 E235 N239 E266 3.4.11.18 0004177,0004239,0005506,0005829,0006508,0008235,0016485,0046872,0046914,0050897,0070006 P9WK19 21465667 286 RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL 3pkd A 1.47 BS02 MN A 2 D131 D142 E269 D128 D139 E266 H114 D131 D142 G204 H205 G208 H212 L215 E238 N242 E269 H111 D128 D139 G201 H202 G205 H209 L212 E235 N239 E266 3.4.11.18 0004177,0004239,0005506,0005829,0006508,0008235,0016485,0046872,0046914,0050897,0070006 P9WK19 21465667 287 RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL 3pkd A 1.47 BS03 Y10 A 1 Y97 H114 D131 D142 T203 H205 F211 H212 E238 E269 Y94 H111 D128 D139 T200 H202 F208 H209 E235 E266 H114 D131 D142 G204 H205 G208 H212 L215 E238 N242 E269 H111 D128 D139 G201 H202 G205 H209 L212 E235 N239 E266 3.4.11.18 0004177,0004239,0005506,0005829,0006508,0008235,0016485,0046872,0046914,0050897,0070006 ic50=0.76uM -logKd/Ki=6.12, IC50=760nM P9WK19 21465667 288 RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL