3pce C 2.06 BS01 3HP O 1 G14 P15 G14 P15 Y79 V114 M122 H125 N127 Y79 V114 M122 H125 N127 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0042952,0051213 P00436 9254599 550 PIELLPETPSQTAGPYVHIGLALEAAGNPTRDQEIWNRLAKPDAPGEHILLLGQVYDGNGHLVRDSFLEVWQADANGEYQDAYNLENAFNSFGRTATTFDAGEWTLHTVKPGVVNNAAGVPMAPHINISLFARGINIHLHTRLYFDDEAQANAKCPVLNLIEQPQRRETLIAKRCEVDGKTAYRFDIRIQGEGETVFFDF 3pce E 2.06 BS01 3HP Q 1 G14 P15 G14 P15 Y79 V114 M122 H125 N127 Y79 V114 M122 H125 N127 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0042952,0051213 P00436 9254599 550 PIELLPETPSQTAGPYVHIGLALEAAGNPTRDQEIWNRLAKPDAPGEHILLLGQVYDGNGHLVRDSFLEVWQADANGEYQDAYNLENAFNSFGRTATTFDAGEWTLHTVKPGVVNNAAGVPMAPHINISLFARGINIHLHTRLYFDDEAQANAKCPVLNLIEQPQRRETLIAKRCEVDGKTAYRFDIRIQGEGETVFFDF 3pce M 2.06 BS01 FE M 1 Y408 Y447 H460 H462 Y105 Y144 H157 H159 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 P00437 9254599 600 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce M 2.06 BS02 3HP M 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM -logKd/Ki=2.00, Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce N 2.06 BS01 FE N 1 Y408 Y447 H460 H462 Y105 Y144 H157 H159 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 P00437 9254599 600 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce N 2.06 BS02 3HP N 1 Y447 W449 R457 H462 I491 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce O 2.06 BS01 FE O 1 Y408 Y447 H460 H462 Y105 Y144 H157 H159 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 P00437 9254599 600 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce O 2.06 BS02 3HP O 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce P 2.06 BS01 FE P 1 Y408 Y447 H460 H462 Y105 Y144 H157 H159 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 P00437 9254599 600 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce P 2.06 BS02 3HP P 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM -logKd/Ki=2.00, Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce Q 2.06 BS01 FE Q 1 Y408 Y447 H460 H462 Y105 Y144 H157 H159 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 P00437 9254599 600 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce Q 2.06 BS02 3HP Q 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce R 2.06 BS01 FE R 1 Y408 Y447 H460 H462 Y105 Y144 H157 H159 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 P00437 9254599 600 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce R 2.06 BS02 3HP R 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE