3oxi A 2.2 BS01 peptide J 0 M159 R165 Y168 S199 D200 C201 W362 M114 R120 Y123 S154 D155 C156 W298 D189 K191 N194 D207 T226 D144 K146 N149 D162 T166 2.7.11.24 0004672,0004707,0005524,0006468 P53779 21071223 154 ~ 163 NQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVREHTIEEWKELIYKEVMN 3oxi A 2.2 BS02 SYY A 1 I70 G71 V78 A91 M146 E147 L148 M149 N152 V196 L206 I25 G26 V33 A46 M101 E102 L103 M104 N107 V151 L161 D189 K191 N194 D207 T226 D144 K146 N149 D162 T166 2.7.11.24 0004672,0004707,0005524,0006468 ic50=2.2uM -logKd/Ki=5.66, IC50=2.2uM IC50=2200nM P53779 21071223 1 NQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVREHTIEEWKELIYKEVMN