3ox3 A 1.8 BS01 ZN A 1 H173 H177 C222 H172 H176 C221 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 21538647 231 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHF 3ox3 A 1.8 BS02 FAD A 1 H11 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 R200 H10 S15 F16 N17 S19 P101 L102 Y103 W104 F105 T146 T147 G148 G149 Y154 E192 R199 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 21538647 232 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHF 3ox3 A 1.8 BS03 4X4 A 1 G68 F126 F178 G67 F125 F177 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 ic50=11nM P16083 21538647 233 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHF 3ox3 A 1.8 BS04 4X4 B 1 W105 F106 G149 M154 I194 W104 F105 G148 M153 I193 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 ic50=11nM P16083 21538647 233 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHF 3ox3 B 1.8 BS01 4X4 A 1 W105 F106 M154 I194 W104 F105 M153 I193 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 ic50=11nM P16083 21538647 233 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3ox3 B 1.8 BS02 ZN B 1 H173 H177 C222 H172 H176 C221 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 21538647 231 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3ox3 B 1.8 BS03 FAD B 1 H11 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 Y155 E193 R200 H10 S15 F16 N17 S19 P101 L102 Y103 W104 F105 T146 T147 G148 Y154 E192 R199 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 P16083 21538647 232 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG 3ox3 B 1.8 BS04 4X4 B 1 G68 F126 G174 F178 G67 F125 G173 F177 G149 Y155 N161 G148 Y154 N160 1.10.5.1 0001512,0003955,0005515,0005654,0005737,0005829,0008270,0009055,0016491,0016661,0031404,0042803,0046872,0070062,0071949,1901662,1904408,1905594 ic50=11nM P16083 21538647 233 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFG