3n9s A 1.85 BS01 TD4 A 1 N23 S49 D82 H83 H180 G181 K184 H210 G211 S213 N253 D255 T256 N23 S49 D82 H83 H180 G181 K184 H210 G211 S213 N253 D255 T256 C69 E70 G136 H180 A226 N253 C69 E70 G136 H180 A226 N253 0004332,0005975,0006096,0008270,0016832,0030388 Ki=0.07uM -logKd/Ki=5.26, Kd=5.5uM 20929256 308 MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKDAVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDNVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI 3n9s A 1.85 BS02 ZN A 1 H83 H180 H210 H83 H180 H210 C69 E70 G136 H180 A226 N253 C69 E70 G136 H180 A226 N253 0004332,0005975,0006096,0008270,0016832,0030388 20929256 309 MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKDAVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDNVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI 3n9s A 1.85 BS03 CA A 1 D104 S106 E134 D104 S106 E134 C69 E70 G136 H180 A226 N253 C69 E70 G136 H180 A226 N253 0004332,0005975,0006096,0008270,0016832,0030388 20929256 310 MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKDAVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDNVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI 3n9s B 1.85 BS01 ZN B 1 H83 H180 H210 H83 H168 H198 C69 E70 G136 H180 A226 N253 C69 E70 G136 H168 A214 N241 0004332,0005975,0006096,0008270,0016832,0030388 20929256 308 MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMAVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDNVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI 3n9s B 1.85 BS02 CA B 1 D104 S106 E134 D104 S106 E134 C69 E70 G136 H180 A226 N253 C69 E70 G136 H168 A214 N241 0004332,0005975,0006096,0008270,0016832,0030388 20929256 309 MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMAVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDNVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI 3n9s B 1.85 BS03 TD4 B 1 N23 S49 D82 H83 H180 G181 K184 H210 G211 S213 N253 D255 T256 N23 S49 D82 H83 H168 G169 K172 H198 G199 S201 N241 D243 T244 C69 E70 G136 H180 A226 N253 C69 E70 G136 H168 A214 N241 0004332,0005975,0006096,0008270,0016832,0030388 Ki=0.07uM -logKd/Ki=5.26, Kd=5.5uM 20929256 311 MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMAVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDNVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI