3lvp A 3.0 BS01 PDR A 1 L1005 G1006 Q1007 A1031 K1033 M1079 M1082 G1085 M1142 L17 G18 Q19 A43 K45 M91 M94 G97 M152 D1135 R1139 N1140 D1153 D145 R149 N150 D163 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 -logKd/Ki=8.70, IC50=2nM P08069 20545947 1 PDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMEPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENK 3lvp B 3.0 BS01 PDR B 1 L1005 G1006 A1031 M1079 L1081 M1082 T1083 G1085 L20 G21 A46 M94 L96 M97 T98 G100 D1135 R1139 N1140 D1153 E1162 D145 R149 N150 D163 E172 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 P08069 20545947 2 VYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEEN 3lvp C 3.0 BS01 PDR C 1 L1005 G1006 V1013 A1031 M1082 T1083 G1085 M1142 L19 G20 V27 A45 M96 T97 G99 M151 D1135 R1139 N1140 D1153 E1162 D144 R148 N149 D162 E171 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 P08069 20545947 3 YVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENK 3lvp D 3.0 BS01 PDR D 1 L1005 E1080 M1082 G1085 M1142 L20 E85 M87 G90 M142 D1135 R1139 N1140 D1153 E1162 D135 R139 N140 D153 E162 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 P08069 20545947 4 VYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEEN