3lj7 A 2.3 BS01 OHO A 1 F192 I238 G239 S241 F160 I206 G207 S209 K142 S217 S218 T236 I238 G239 G240 S241 F244 K110 S185 S186 T204 I206 G207 G208 S209 F212 3.1.1.-,3.5.1.99 0000139,0004040,0005515,0005543,0005783,0005789,0005794,0006631,0008289,0009062,0016020,0016042,0016787,0016788,0017064,0031090,0042802,0045907,0047372,0052651,0098793,0098794,0098978,0150036 -logKd/Ki=8.34, IC50=4.6nM P97612 20493882 1 GRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSTGGLFSDGGRSFLQNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNNMRPRSAEKLWKLQHEIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQKQ 3lj7 B 2.3 BS01 OHO B 1 F192 S193 I238 G239 S241 F161 S162 I207 G208 S210 K142 S217 S218 T236 I238 G239 G240 S241 F244 K111 S186 S187 T205 I207 G208 G209 S210 F213 3.1.1.-,3.5.1.99 0000139,0004040,0005515,0005543,0005783,0005789,0005794,0006631,0008289,0009062,0016020,0016042,0016787,0016788,0017064,0031090,0042802,0045907,0047372,0052651,0098793,0098794,0098978,0150036 P97612 20493882 1 TGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSTGGLFSDGGRSFLQNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNNMRPRSAEKLWKLQHEIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQKQP