3l0v A 1.75 BS01 ZN A 1 H405 H409 H415 H186 H190 H196 3.4.24.86 0004222,0006508,0008237 P78536 20172725 1 ADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS 3l0v A 1.75 BS02 724 A 1 T347 L348 G349 L401 V402 H405 E406 H409 H415 P437 A439 T132 L133 G134 L182 V183 H186 E187 H190 H196 P218 A220 3.4.24.86 0004222,0006508,0008237 Ki=23nM -logKd/Ki=7.64, Ki=23nM Ki=23nM P78536 20172725 485 ADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS 3l0v B 1.75 BS01 ZN B 1 H405 H409 H415 H184 H188 H194 3.4.24.86 0004222,0006508,0008237 P78536 20172725 2 PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQER 3l0v B 1.75 BS02 724 B 1 T347 L348 G349 L401 V402 H405 E406 H409 H415 P437 A439 T128 L129 G130 L180 V181 H184 E185 H188 H194 P216 A218 3.4.24.86 0004222,0006508,0008237 Ki=23nM Ki=23nM P78536 20172725 485 PMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQER