3krw A 2.9 BS01 BA1 A 1 G198 R199 G200 G201 F202 G203 V205 A218 K220 E239 D272 L273 A321 L324 S334 D335 G167 R168 G169 G170 F171 G172 V174 A187 K189 E208 D241 L242 A290 L293 S303 D304 D317 K319 N322 D335 K344 T353 D286 K288 N291 D304 K313 T322 2.7.11.15 0001664,0002026,0002029,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0005929,0006468,0007165,0007186,0007213,0007217,0007507,0016020,0016310,0018105,0019079,0031623,0031694,0031755,0032473,0033605,0042995,0045202,0045988,0046718,0047696,0060048,0098793,0098794,1901081 -logKd/Ki=7.38, IC50=42nM IC50=42nM P25098 20128603 690 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPREEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSP 3krw A 2.9 BS02 MG A 1 H348 E360 V361 V366 Y368 H317 E329 V330 V335 Y337 D317 K319 N322 D335 K344 T353 D286 K288 N291 D304 K313 T322 2.7.11.15 0001664,0002026,0002029,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0005929,0006468,0007165,0007186,0007213,0007217,0007507,0016020,0016310,0018105,0019079,0031623,0031694,0031755,0032473,0033605,0042995,0045202,0045988,0046718,0047696,0060048,0098793,0098794,1901081 P25098 20128603 691 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPREEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSP