3kba A 2.0 BS01 WOW A 1 L715 L718 N719 L721 M759 V760 F778 F794 M801 L887 Y890 C891 F905 L29 L32 N33 L35 M73 V74 F92 F106 M113 L198 Y201 C202 F216 ? ic50=16nM -logKd/Ki=7.80, IC50=16nM IC50=16nM, EC50=25nM P06401 19926282 1 QLIPPLINLLMSIEPDVIYAGHDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKEFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHK 3kba B 2.0 BS01 WOW B 1 L718 N719 L721 G722 M759 F778 F794 M801 L887 Y890 C891 T894 F905 L37 N38 L40 G41 M78 F97 F113 M120 L206 Y209 C210 T213 F224 ? ic50=16nM IC50=16nM, EC50=25nM P06401 19926282 2 QLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFH