3kb7 A 2.5 BS01 071 A 1 L59 C67 A80 K82 C133 R136 S137 E140 F183 D194 L21 C29 A42 K44 C95 R98 S99 E102 F145 D156 D176 K178 G180 N181 D194 T214 D138 K140 G142 N143 D156 T176 2.7.11.21 0004672,0005524,0006468 ic50=0.007uM -logKd/Ki=8.15, IC50=7nM IC50=7nM P53350 20397705 1 EIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIA 3kb7 A 2.5 BS02 ZN A 1 H93 C212 H55 C174 D176 K178 G180 N181 D194 T214 D138 K140 G142 N143 D156 T176 2.7.11.21 0004672,0005524,0006468 P53350 20397705 346 EIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIA