3ii4 A 2.42 BS01 FAD A 1 L9 G10 G12 P13 G14 V32 E33 P34 Y36 G39 V40 C41 G45 C46 K50 Y112 G113 A141 T142 G143 Y161 I182 Y276 G308 D309 Q315 L316 A317 L8 G9 G11 P12 G13 V31 E32 P33 Y35 G38 V39 C40 G44 C45 K49 Y111 G112 A140 T141 G142 Y160 I181 Y275 G307 D308 Q314 L315 A316 W37 C41 C46 S49 A181 E185 H441 H443 E448 W36 C40 C45 S48 A180 E184 H440 H442 E447 1.8.1.4 0004148,0004591,0005515,0005576,0005737,0005829,0005886,0015036,0016209,0016491,0016655,0016668,0035375,0045254,0045454,0050660,0070404,0098869 P9WHH9 20078138 480 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 3ii4 A 2.42 BS02 3II A 1 R147 A181 I182 E185 N209 E210 F269 R288 G312 Q315 L316 R347 A348 R146 A180 I181 E184 N208 E209 F268 R287 G311 Q314 L315 R346 A347 W37 C41 C46 S49 A181 E185 H441 H443 E448 W36 C40 C45 S48 A180 E184 H440 H442 E447 1.8.1.4 0004148,0004591,0005515,0005576,0005737,0005829,0005886,0015036,0016209,0016491,0016655,0016668,0035375,0045254,0045454,0050660,0070404,0098869 Ki=865nM P9WHH9 20078138 465 THYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 3ii4 B 2.42 BS01 FAD B 1 L9 G10 G12 P13 G14 V32 E33 P34 Y36 G39 V40 C41 G45 C46 K50 Y112 G113 A141 T142 G143 Y161 I182 Y276 G308 D309 Q315 L316 A317 L9 G10 G12 P13 G14 V32 E33 P34 Y36 G39 V40 C41 G45 C46 K50 Y112 G113 A141 T142 G143 Y161 I182 Y276 G308 D309 Q315 L316 A317 W37 C41 C46 S49 A181 E185 H441 H443 E448 W37 C41 C46 S49 A181 E185 H441 H443 E448 1.8.1.4 0004148,0004591,0005515,0005576,0005737,0005829,0005886,0015036,0016209,0016491,0016655,0016668,0035375,0045254,0045454,0050660,0070404,0098869 P9WHH9 20078138 580 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF 3ii4 B 2.42 BS02 3II B 1 A181 I182 E185 N209 P271 R288 G312 L313 L314 Q315 L316 R347 A348 A181 I182 E185 N209 P271 R288 G312 L313 L314 Q315 L316 R347 A348 W37 C41 C46 S49 A181 E185 H441 H443 E448 W37 C41 C46 S49 A181 E185 H441 H443 E448 1.8.1.4 0004148,0004591,0005515,0005576,0005737,0005829,0005886,0015036,0016209,0016491,0016655,0016668,0035375,0045254,0045454,0050660,0070404,0098869 Ki=865nM P9WHH9 20078138 465 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF