3hxc B 1.95 BS01 ZN B 1 D238 C240 H290 D230 C232 H282 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H182 R224 K227 D230 C232 Y233 D272 D279 H282 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 Q08603 19894725 332 QKDVTIKSDAPDTLLLEKHADYIASYGSYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 3hxc B 1.95 BS02 CA B 1 H64 M66 H56 M58 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H182 R224 K227 D230 C232 Y233 D272 D279 H282 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 Q08603 19894725 333 QKDVTIKSDAPDTLLLEKHADYIASYGSYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 3hxc B 1.95 BS03 BD6 B 1 W52 R144 F147 G192 Q193 D238 C240 W244 F289 W44 R136 F139 G184 Q185 D230 C232 W236 F281 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H182 R224 K227 D230 C232 Y233 D272 D279 H282 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 -logKd/Ki=5.28, IC50=5.2uM Q08603 19894725 334 QKDVTIKSDAPDTLLLEKHADYIASYGSYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS