3h0z A 2.92 BS01 45B A 1 V147 L194 A213 G216 T217 Y219 K224 E260 L263 V20 L67 A86 G89 T90 Y92 K97 E133 L136 D256 K258 E260 N261 D274 T292 D129 K131 E133 N134 D147 T152 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 -logKd/Ki=8.37, IC50=4.3nM IC50=4.3nM O14965 19402633 1 WALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 3h0z B 2.92 BS01 45B B 1 L139 V147 A213 G216 T217 Y219 R220 L263 L14 V16 A82 G85 T86 Y88 R89 L132 D256 K258 E260 N261 D274 T292 D125 K127 E129 N130 D143 T144 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 IC50=4.3nM O14965 19402633 1 RQWALEDFEIGRPLGVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 3h0z C 2.92 BS01 45B C 1 V147 A160 A213 L215 G216 T217 Y219 E260 L263 V22 A35 A88 L90 G91 T92 Y94 E135 L138 D256 K258 E260 N261 D274 T292 D131 K133 E135 N136 D149 T150 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 IC50=4.3nM O14965 19402633 1 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS