3h0w A 1.81 BS01 N8M A 1 F223 C226 G227 Y228 I244 T245 E247 F146 C149 G150 Y151 I167 T168 E170 S229 H243 S152 H166 4.1.1.50 0004014,0006597,0008295 ic50=600nM -logKd/Ki=6.22, IC50=600nM IC50=600nM P17707 19527050 368 SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQKIEGFKRLDCQSAMFNDYNFVFTSFAK 3h0w A 1.81 BS02 PYR A 1 S69 K80 H243 S1 K12 H166 S229 H243 S152 H166 4.1.1.50 0004014,0006597,0008295 P17707 19527050 68 SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQKIEGFKRLDCQSAMFNDYNFVFTSFAK 3h0w B 1.81 BS01 N8M A 1 F7 S66 E67 F4 S60 E61 E67 E61 4.1.1.50 0004014,0008295 -logKd/Ki=6.22, IC50=600nM IC50=600nM P17707 19527050 368 AHFFEGTEKLLEVWFSRQQPQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE 3h0w B 1.81 BS02 PYR A 1 V64 L65 V58 L59 E67 E61 4.1.1.50 0004014,0008295 P17707 19527050 68 AHFFEGTEKLLEVWFSRQQPQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE