3g3d A 1.7 BS01 5FU A 1 S68 D70 H94 K125 M182 S183 P228 Q241 Y243 G261 R262 S34 D36 H60 K91 M148 S149 P194 Q207 Y209 G227 R228 2.4.2.10,4.1.1.23 0004590,0006207,0044205 -logKd/Ki=4.74, Ki=18.2uM Ki=98000nM P11172 19260677 3000 ELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG 3g3d A 1.7 BS02 5FU B 1 D128 I129 T132 D94 I95 T98 2.4.2.10,4.1.1.23 0004590,0006207,0044205 -logKd/Ki=4.74, Ki=18.2uM Ki=98000nM P11172 19260677 3000 ELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG 3g3d B 1.7 BS01 5FU A 1 D128 I129 T132 D97 I98 T101 2.4.2.10,4.1.1.23 0004590,0006207,0044205 -logKd/Ki=4.74, Ki=18.2uM Ki=98000nM P11172 19260677 3000 APKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG 3g3d B 1.7 BS02 5FU B 1 S68 D70 H94 K125 M182 S183 P228 Q241 Y243 G261 R262 S37 D39 H63 K94 M151 S152 P197 Q210 Y212 G230 R231 2.4.2.10,4.1.1.23 0004590,0006207,0044205 -logKd/Ki=4.74, Ki=18.2uM Ki=98000nM P11172 19260677 3000 APKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLG