3g0x A 1.8 BS01 FMN A 1 A96 G97 K100 S120 N145 N181 N212 K255 N284 T285 S305 G306 V333 G334 G335 L355 Y356 T357 A60 G61 K64 S84 N109 N145 N176 K219 N248 T249 S269 G270 V297 G298 G299 L319 Y320 T321 G119 N145 F149 S215 N217 T218 K255 N284 G83 N109 F113 S179 N181 T182 K219 N248 1.3.5.2 0004151,0004152,0005515,0005654,0005737,0005739,0005743,0005829,0006207,0006221,0006225,0009220,0016020,0016491,0016627,0044205,0106430 Q02127 19351152 398 DERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR 3g0x A 1.8 BS02 MD7 A 1 M43 L46 P52 H56 A59 L68 R136 Y356 T360 P364 M10 L13 P19 H23 A26 L35 R100 Y320 T324 P328 G119 N145 F149 S215 N217 T218 K255 N284 G83 N109 F113 S179 N181 T182 K219 N248 1.3.5.2 0004151,0004152,0005515,0005654,0005737,0005739,0005743,0005829,0006207,0006221,0006225,0009220,0016020,0016491,0016627,0044205,0106430 ic50=0.053uM Ki=7nM, IC50=53nM Q02127 19351152 2 DERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR