3fup A 2.4 BS01 MI1 A 1 L855 G856 K857 G858 G861 V863 A880 Y931 L932 L983 G993 D994 L13 G14 K15 G16 G19 V21 A38 Y85 L86 L137 G147 D148 D976 A978 R980 N981 D994 S1016 D130 A132 R134 N135 D148 S170 2.7.10.2 0004672,0004713,0005524,0006468 ic50=21.7nM -logKd/Ki=7.66, IC50=21.7nM IC50=77nM, EC50=93nM, Kd=5nM, Ki=0.700000nM O60674 19361440 1 QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDQMAG 3fup B 2.4 BS01 MI1 B 1 G856 K857 G858 G861 S862 V863 A880 M929 Y931 L932 L983 G993 D994 G17 K18 G19 G22 S23 V24 A41 M86 Y88 L89 L140 G150 D151 D976 A978 R980 N981 D994 S1016 D133 A135 R137 N138 D151 S173 2.7.10.2 0004672,0004713,0005524,0006468 ic50=21.7nM IC50=77nM, EC50=93nM, Kd=5nM, Ki=0.700000nM O60674 19361440 1 DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDQMAG