3ftq A 2.9 BS01 MG A 1 S51 T78 S18 T30 ? 0005525,0051301 P42208 19805342 371 KGFEFTLMVVGESGLGKSTLINSLFKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAEEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLK 3ftq A 2.9 BS02 GNP A 1 S46 G49 K50 S51 T52 T78 G104 K183 D185 V240 G241 R256 S13 G16 K17 S18 T19 T30 G56 K134 D136 V189 G190 R205 ? 0005525,0051301 -logKd/Ki=5.33, Kd=4.7uM P42208 19805342 372 KGFEFTLMVVGESGLGKSTLINSLFKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAEEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLK 3ftq B 2.9 BS01 MG B 1 S51 T78 S18 T35 ? 0005525,0051301 P42208 19805342 371 KGFEFTLMVVGESGLGKSTLINSLFLTDLYKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAEDFKEQTRLLKASIPFSVVGSNQLIEVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLK 3ftq B 2.9 BS02 GNP B 1 S46 G47 G49 K50 S51 T52 R77 T78 G104 K183 D185 V240 G241 R256 S13 G14 G16 K17 S18 T19 R34 T35 G61 K140 D142 V192 G193 R203 ? 0005525,0051301 P42208 19805342 372 KGFEFTLMVVGESGLGKSTLINSLFLTDLYKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAEDFKEQTRLLKASIPFSVVGSNQLIEVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLK 3ftq C 2.9 BS01 MG C 1 S51 T78 S18 T31 ? 0005525,0051301 P42208 19805342 371 KGFEFTLMVVGESGLGKSTLINSLFLTIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLK 3ftq C 2.9 BS02 GNP C 1 S46 G47 G49 K50 S51 T52 R77 T78 G104 K183 D185 V240 G241 R256 S13 G14 G16 K17 S18 T19 R30 T31 G57 K133 D135 V185 G186 R201 ? 0005525,0051301 P42208 19805342 372 KGFEFTLMVVGESGLGKSTLINSLFLTIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLK 3ftq D 2.9 BS01 MG D 1 S51 T78 S17 T29 ? 0005525,0051301 P42208 19805342 371 GFEFTLMVVGESGLGKSTLINSLFLTERTVQIEASTVEIEERGVKLRLTVVDTPGYGAINCRDCFKTIISYIDEQFERYLHDESGHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERL 3ftq D 2.9 BS02 GNP D 1 S46 G47 G49 K50 S51 T52 R77 T78 G104 K183 D185 V240 G241 R256 S12 G13 G15 K16 S17 T18 R28 T29 G55 K129 D131 V179 G180 R195 ? 0005525,0051301 P42208 19805342 372 GFEFTLMVVGESGLGKSTLINSLFLTERTVQIEASTVEIEERGVKLRLTVVDTPGYGAINCRDCFKTIISYIDEQFERYLHDESGHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHSIKIYHLPDAFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERL