3fne A 1.98 BS01 NAD A 1 G14 I16 S20 I21 F41 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 P193 I194 T196 G13 I15 S19 I20 F40 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 P192 I193 T195 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 19130456 300 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 3fne A 1.98 BS02 8PC A 1 G96 M98 F149 Y158 M161 A198 M199 G95 M97 F148 Y157 M160 A197 M198 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 ic50=29nM P9WGR1 19130456 400 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 3fne B 1.98 BS01 NAD B 1 G14 I16 S20 I21 F41 L63 D64 V65 S94 I95 M147 D148 F149 K165 A191 P193 I194 T196 A198 G13 I15 S19 I20 F40 L62 D63 V64 S93 I94 M146 D147 F148 K164 A190 P192 I193 T195 A197 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 19130456 310 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 3fne B 1.98 BS02 8PC B 1 G96 F97 M98 M103 F149 Y158 A198 I215 E219 G95 F96 M97 M102 F148 Y157 A197 I200 E204 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 ic50=29nM P9WGR1 19130456 410 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 3fne C 1.98 BS01 NAD C 1 G14 I16 S20 I21 F41 D64 V65 S94 I95 G96 I122 M147 D148 K165 A191 P193 I194 T196 A198 G13 I15 S19 I20 F40 D63 V64 S93 I94 G95 I121 M146 D147 K164 A190 P192 I193 T195 A197 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 19130456 320 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 3fne C 1.98 BS02 8PC C 1 G96 M98 F149 Y158 M161 A198 I202 L218 G95 M97 F148 Y157 M160 A197 I201 L214 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 ic50=29nM P9WGR1 19130456 420 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 3fne D 1.98 BS01 NAD D 1 G14 I16 S20 I21 F41 D64 V65 S94 I95 I122 M147 D148 F149 K165 A191 P193 I194 T196 A198 G13 I15 S19 I20 F40 D63 V64 S93 I94 I121 M146 D147 F148 K164 A190 P192 I193 T195 A197 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 P9WGR1 19130456 330 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 3fne D 1.98 BS02 8PC D 1 G96 F97 M98 F149 Y158 A198 M199 I215 G95 F96 M97 F148 Y157 A197 M198 I206 Y158 K165 Y157 K164 1.3.1.9 0004318,0005504,0005886,0006633,0009274,0016491,0030497,0046677,0050343,0070403,0071768 ic50=29nM P9WGR1 19130456 430 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL