3fi3 A 2.2 BS01 JK2 A 1 I70 A91 K93 I124 M146 L148 M149 D150 A151 L206 I26 A42 K44 I75 M97 L99 M100 D101 A102 L157 D189 K191 N194 D207 T226 D140 K142 N145 D158 T165 2.7.11.24 0004672,0004707,0005524,0006468 ic50=12nM -logKd/Ki=7.92, IC50=12nM IC50=9.0nM P53779 19261605 600 DNQFYSVEVGDSTFTVLKRYQNLKPIGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYPPQIYDKQLDEREHTIEEWKELIYKEVMNS