3fhe A 2.16 BS01 ZN A 1 H295 H299 E318 H292 H296 E315 E271 H295 E296 H299 E318 D375 Y383 E268 H292 E293 H296 E315 D372 Y380 3.3.2.6,3.4.11.4 0003723,0004177,0004301,0004463,0005515,0005576,0005634,0005654,0005737,0005829,0006508,0006629,0006691,0008233,0008237,0008270,0010043,0019370,0019538,0043171,0043434,0045148,0046872,0060509,0070006,0070062,1904724,1904813 P09960 19950900 1001 VDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 3fhe A 2.16 BS02 28P A 1 Q136 A137 Y267 G269 M270 E271 H295 E296 H299 W311 F314 E318 V367 P374 A377 Y378 Y383 Q133 A134 Y264 G266 M267 E268 H292 E293 H296 W308 F311 E315 V364 P371 A374 Y375 Y380 E271 H295 E296 H299 E318 D375 Y383 E268 H292 E293 H296 E315 D372 Y380 3.3.2.6,3.4.11.4 0003723,0004177,0004301,0004463,0005515,0005576,0005634,0005654,0005737,0005829,0006508,0006629,0006691,0008233,0008237,0008270,0010043,0019370,0019538,0043171,0043434,0045148,0046872,0060509,0070006,0070062,1904724,1904813 -logKd/Ki=8.60, IC50=2.5nM IC50=6.0nM, Kd=350nM, Ki=3.0nM P09960 19950900 612 VDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD