3f17 A 1.1 BS01 ZN A 1 H218 H222 H228 H113 H117 H123 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 264 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3f17 A 1.1 BS02 ZN A 2 H168 D170 H183 H196 H63 D65 H78 H91 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 265 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3f17 A 1.1 BS03 CA A 1 D158 G190 I191 G192 D194 D53 G85 I86 G87 D89 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 266 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3f17 A 1.1 BS04 CA A 2 D124 E199 E201 D19 E94 E96 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 267 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3f17 A 1.1 BS05 CA A 3 D175 G176 G178 I180 D198 E201 D70 G71 G73 I75 D93 E96 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 268 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3f17 A 1.1 BS06 HS4 A 1 I180 A182 L214 T215 H218 E219 H222 H228 V235 P238 Y240 I75 A77 L109 T110 H113 E114 H117 H123 V130 P133 Y135 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 Kd=2.36nM -logKd/Ki=8.63, Kd=2.36nM Ki=2.0nM P39900 17269766 0 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG