3eks A 1.8 BS01 ATP A 1 G13 S14 G15 K18 G156 D157 G158 V159 G182 K213 E214 G302 M305 Y306 G12 S13 G14 K17 G155 D156 G157 V158 G181 K212 E213 G301 M304 Y305 3.6.4.- 0000281,0005515,0005524,0005737,0005856,0006338,0007291,0016787,0030723,0031011,0032507,0035060,0035148 P10987 18938176 800 DEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 3eks A 1.8 BS02 CA A 1 Q263 S265 Q262 S264 3.6.4.- 0000281,0005515,0005524,0005737,0005856,0006338,0007291,0016787,0030723,0031011,0032507,0035060,0035148 P10987 18938176 902 DEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 3eks A 1.8 BS03 CY9 A 1 Y133 A135 I136 Y143 Y169 A170 P172 M355 F375 Y132 A134 I135 Y142 Y168 A169 P171 M354 F374 3.6.4.- 0000281,0005515,0005524,0005737,0005856,0006338,0007291,0016787,0030723,0031011,0032507,0035060,0035148 -logKd/Ki=5.70, Kd=2uM P10987 18938176 903 DEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF