3d27 A 2.2 BS01 MN A 1 D108 H171 E204 E235 D105 H168 E201 E232 H79 D97 D108 H171 R175 H178 Q182 E204 N208 Q233 E235 H76 D94 D105 H168 R172 H175 Q179 E201 N205 Q230 E232 3.4.11.18 0004177,0004239,0005829,0006508,0008198,0008235,0046872,0046914,0070006 P0AE18 18785729 1 SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE 3d27 A 2.2 BS02 MN A 2 D97 D108 E235 D94 D105 E232 H79 D97 D108 H171 R175 H178 Q182 E204 N208 Q233 E235 H76 D94 D105 H168 R172 H175 Q179 E201 N205 Q230 E232 3.4.11.18 0004177,0004239,0005829,0006508,0008198,0008235,0046872,0046914,0070006 P0AE18 18785729 2 SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE 3d27 A 2.2 BS03 W29 A 1 Y62 Y65 H79 D97 D108 H171 H178 E204 Y59 Y62 H76 D94 D105 H168 H175 E201 H79 D97 D108 H171 R175 H178 Q182 E204 N208 Q233 E235 H76 D94 D105 H168 R172 H175 Q179 E201 N205 Q230 E232 3.4.11.18 0004177,0004239,0005829,0006508,0008198,0008235,0046872,0046914,0070006 ic50=55.7uM -logKd/Ki=4.25, IC50=55.7uM P0AE18 18785729 265 SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE