3d0e A 2.0 BS01 G93 A 1 V166 A179 K181 E200 L204 F227 M229 Y231 A232 E236 E279 M282 D293 F294 F439 V21 A34 K36 E55 L59 F82 M84 Y86 A87 E91 E134 M137 D148 F149 F294 D275 K277 N280 D293 T313 D130 K132 N135 D148 T168 2.7.11.1 0004672,0004674,0005524,0006468 ic50=13nM -logKd/Ki=8.40, Ki=4nM IC50=13nM, Kd=2.1nM, Ki=4nM P31751 18800763 1 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDQRTHFPQFDYSASIR 3d0e B 2.0 BS01 G93 B 1 V166 A179 K181 E200 L204 F227 M229 Y231 A232 E236 E279 M282 D293 F294 F439 F443 V21 A34 K36 E55 L59 F82 M84 Y86 A87 E91 E134 M137 D148 F149 F294 F298 D275 K277 N280 D293 T313 D130 K132 N135 D148 T168 2.7.11.1 0004672,0004674,0005524,0006468 ic50=13nM IC50=13nM, Kd=2.1nM, Ki=4nM P31751 18800763 2 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDQRTHFPQFDYSASIR