3cs9 A 2.21 BS01 NIL A 1 L248 Y253 A269 K271 E286 M290 I313 T315 F317 M318 H361 A380 D381 F382 L16 Y21 A37 K39 E50 M54 I77 T79 F81 M82 H125 A144 D145 F146 D363 A365 R367 N368 D381 P402 D127 A129 R131 N132 D145 P166 2.7.10.2 0004672,0004713,0005524,0006468 ic50<33uM Kd=10nM, IC50=20nM, Ki=1nM P00519 15710326 600 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES 3cs9 B 2.21 BS01 NIL B 1 Y253 A269 K271 E286 V289 M290 V299 I313 T315 F317 M318 H361 A380 D381 F382 Y21 A37 K39 E51 V54 M55 V64 I78 T80 F82 M83 H126 A145 D146 F147 D363 A365 R367 N368 D381 P402 D128 A130 R132 N133 D146 P149 2.7.10.2 0004672,0004713,0005524,0006468 ic50<33uM Kd=10nM, IC50=20nM, Ki=1nM P00519 15710326 600 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES 3cs9 C 2.21 BS01 NIL C 1 L248 Y253 A269 K271 E286 V289 M290 I313 T315 F317 M318 H361 A380 D381 F382 L17 Y22 A38 K40 E50 V53 M54 I77 T79 F81 M82 H125 A144 D145 F146 D363 A365 R367 N368 D381 P402 D127 A129 R131 N132 D145 P148 2.7.10.2 0004672,0004713,0005524,0006468 ic50<33uM Kd=10nM, IC50=20nM, Ki=1nM P00519 15710326 600 YDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMF 3cs9 D 2.21 BS01 NIL D 1 L248 Y253 A269 K271 E286 V289 M290 T315 F317 M318 H361 A380 D381 F382 L16 Y21 A32 K34 E49 V52 M53 T78 F80 M81 H124 A143 D144 F145 D363 A365 R367 N368 D381 P402 D126 A128 R130 N131 D144 P165 2.7.10.2 0004672,0004713,0005524,0006468 ic50<33uM Kd=10nM, IC50=20nM, Ki=1nM P00519 15710326 600 DKWEMERTDITMKHKLGGGQYGEVYEGVWTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES