3clx A 2.7 BS01 X22 D 1 E318 I342 E63 I87 2.3.2.27 IC50=290nM P98170 18851976 600 LPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx A 2.7 BS02 ZN A 1 C300 C303 H320 C327 C45 C48 H65 C72 2.3.2.27 P98170 18851976 502 LPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx A 2.7 BS03 X22 A 1 K297 G306 L307 T308 D309 E314 Q319 W323 K42 G51 L52 T53 D54 E59 Q64 W68 2.3.2.27 IC50=290nM P98170 18851976 600 LPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx B 2.7 BS01 ZN B 1 C300 C303 H320 C327 C47 C50 H67 C74 2.3.2.27 P98170 18851976 502 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx B 2.7 BS02 X22 B 1 K297 G306 L307 T308 D309 W310 E314 Q319 W323 K44 G53 L54 T55 D56 W57 E61 Q66 W70 2.3.2.27 IC50=290nM P98170 18851976 600 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx C 2.7 BS01 ZN C 1 C300 C303 H320 C327 C45 C48 H65 C72 2.3.2.27 P98170 18851976 502 LPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLV 3clx C 2.7 BS02 X22 C 1 E337 N340 H343 L344 S347 E82 N85 H88 L89 S92 2.3.2.27 IC50=290nM P98170 18851976 700 LPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLV 3clx C 2.7 BS03 X22 C 2 K297 G306 L307 T308 W310 E314 W323 Y324 K42 G51 L52 T53 W55 E59 W68 Y69 2.3.2.27 IC50=290nM P98170 18851976 600 LPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLV 3clx C 2.7 BS04 X22 C 3 C303 K322 W323 Y324 P325 C48 K67 W68 Y69 P70 2.3.2.27 IC50=290nM P98170 18851976 701 LPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLV 3clx D 2.7 BS01 ZN D 1 C300 C303 H320 C327 C47 C50 H67 C74 2.3.2.27 P98170 18851976 502 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx D 2.7 BS02 X22 D 1 G306 L307 T308 D309 E314 W323 G53 L54 T55 D56 E61 W70 2.3.2.27 IC50=290nM P98170 18851976 600 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx D 2.7 BS03 X22 B 1 E349 L352 E96 L99 2.3.2.27 IC50=290nM P98170 18851976 600 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx D 2.7 BS04 X22 C 1 R258 K322 W323 Y324 R5 K69 W70 Y71 2.3.2.27 IC50=290nM P98170 18851976 700 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 3clx D 2.7 BS05 X22 C 3 E337 N340 H343 L344 S347 E84 N87 H90 L91 S94 2.3.2.27 IC50=290nM P98170 18851976 701 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR